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Molecular Rewiring in TNNT2-Linked Hypertrophic Cardiomyopathy hiPSC-Derived Cardiomyocytes upon Metabolic Maturation

2025-09-14

Abstract excerpt

Human induced pluripotent stem cell–derived cardiomyocytes (hiPSC-CMs) are widely used to model cardiac development and inherited cardiomyopathies, yet their immature metabolic state limits interpretation of disease-associated molecular programs. While multiple strategies promote structural and functional maturation, less is known about the molecular regulation of metabolic maturation as a distinct developmental t...

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Literature Corpus work
df90017c-c0b2-55c0-aad2-b6582b2c97ce
DOI
10.1101/2025.09.14.676131
Open publication

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Molecular Rewiring in TNNT2-Linked Hypertrophic Cardiomyopathy hiPSC-Derived Cardiomyocytes upon Metabolic MaturationDOI 10.1101/2025.09.14.676131
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