Article

Lipid availability influences the metabolic maturation of human pluripotent stem cell-derived cardiomyocytes

2020-03-15

Abstract excerpt

<h4>Objectives</h4> Pluripotent stem cell-derived cardiomyocytes are phenotypically immature, which limits their utility in downstream applications. Metabolism is dramatically reprogramed during cardiac maturation in vivo and presents a potential avenue to drive in vitro maturation. We aimed to identify and address metabolic bottlenecks in the generation of human pluripotent stem cell (hPSC)-derived cardiomyocy...

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Literature Corpus work: ec2fcdd6-602f-5bb3-8c32-52b7d32afefc
DOI: 10.1101/2020.03.14.991927

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