Article

Hominoid-specific transposable elements rewired the expression of neural crest migration genes

2025-04-06

Abstract excerpt

Craniofacial development is evolutionarily conserved, yet subtle changes in its regulatory network drive species-specific traits. Transposable elements (TEs) contribute to genome evolution, but their role in cranial neural crest cells (CNCCs) remains unclear. Here, we investigate the domestication of hominoid-specific TEs (LTR5Hs and SVAs) as enhancers during human CNCC specification, a process critical for verteb...

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Literature Corpus work: 772f698d-0ef4-593e-8e0b-ac0144effc2b
DOI: 10.1101/2025.04.04.647334

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