Article
The impact of transposable elements on mammalian development.
Development (Cambridge, England) - 15 Nov 2016
Garcia-Perez Jose L, Widmann Thomas J, Adams Ian R
Abstract excerpt
Despite often being classified as selfish or junk DNA, transposable elements (TEs) are a group of abundant genetic sequences that have a significant impact on mammalian development and genome regulation. In recent years, our understanding of how pre-existing TEs affect genome architecture, gene regulatory networks and protein function during mammalian embryogenesis has dramatically expanded. In addition, the...
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