Article

Molecular determinants of metazoan tricRNA biogenesis

2018-12-17

Abstract excerpt

<h4>ABSTRACT</h4> Mature tRNAs are generated by multiple post-transcriptional processing steps, which can include intron removal. Recently, our laboratory discovered a new class of metazoan circular RNAs formed by ligation of excised tRNA introns; we termed these molecules tRNA intronic circular (tric)RNAs. To investigate the mechanism of tricRNA biogenesis, we generated constructs that replace the native introns...

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Literature Corpus work: df4539c8-4c1c-5fbf-a2dc-b7f1a5d363f6
DOI: 10.1101/497545

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