Article
m6A-dependent circular RNA formation mediates tau-induced neurotoxicity
2024-01-25
Abstract excerpt
<h4>ABSTRACT</h4> Circular RNAs (circRNAs), covalently closed RNA molecules that form due to back-splicing of RNA transcripts, have recently been implicated in Alzheimer’s disease and related tauopathies. circRNAs are regulated by N 6 -methyladenosine (m 6 A) RNA methylation, can serve as “sponges” for proteins and RNAs, and can be translated into protein via a cap-independent mechanism. Mechanisms underlying c...
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Identifiers and source
- Literature Corpus work
- e1e03495-3c50-55a3-87fb-dd0786e6de1b
- DOI
- 10.1101/2024.01.25.577211