Article

An RNA Splicing System that Excises Transposons from Animal mRNAs

2025-02-17

Abstract excerpt

All genomes harbor mobile genetic parasites called transposable elements (TEs). Here we describe a system, which we term SOS splicing, that protects C. elegans and human genes from DNA transposon-mediated disruption by excising these TEs from host mRNAs. SOS splicing, which operates independently of the spliceosome, is a pattern recognition system triggered by base-pairing of inverted terminal repeat elements, wh...

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Literature Corpus work: eca4f65b-ea6e-5c9e-b559-86f39339175f
DOI: 10.1101/2025.02.14.638102

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