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Discovering Selected Antibodies From Deep-Sequenced Phage-Display Antibody Library Using ATTILA

1 Jan 2020

Abstract excerpt

Phage display is a powerful technique to select high-affinity antibodies for different purposes, including biopharmaceuticals. Next-generation sequencing (NGS) presented itself as a robust solution, making it possible to assess billions of sequences of the variable domains from selected sublibraries. Handling this process, a central difficulty is to find the selected clones. Here, we present the AutomaTed Tool...

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PMID: 32425512
DOI: 10.1177/1177932220915240

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