Article

High-throughput protein binder discovery by rapid in vivo selection

2025-01-06

Abstract excerpt

Proteins that selectively bind to a target of interest are foundational components of research pipelines 1,2 , diagnostics 3 , and therapeutics 4 . Current immunization-based 5,6 , display-based 7–14 , and computational approaches 15–17,18 for discovering binders are laborious and time-consuming – taking months or more, suffer from high false positives – necessitating extensive secondary screening, and have...

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Literature Corpus work: fcdbbbdd-1e85-50ab-8234-983a607a850c
DOI: 10.1101/2025.01.06.631531

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