Article

Core binding factor leukemia hijacks T-cell prone PU.1 antisense promoter

2020-05-31

Abstract excerpt

<h4>Summary paragraph</h4> The blood system serves as a key model for cell differentiation and cancer. It is orchestrated by precise spatiotemporal expression of the hematopoietic master regulator PU.1 1–4 . PU.1 gene expression is regulated through enhancer-promoter interactions within a topologically associated domain (TAD) 5,6 . PU.1 levels increase during myeloid differentiation while failure to do so resul...

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Literature Corpus work: df013a81-f384-5680-924e-23612c5d1ed9
DOI: 10.1101/2020.05.29.120857

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