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Article

RUNX1: A MicroRNA Hub in Normal and Malignant Hematopoiesis

14 Jan 2013

Abstract excerpt

Hematopoietic development is orchestrated by gene regulatory networks that progressively induce lineage-specific transcriptional programs. To guarantee the appropriate level of complexity, flexibility, and robustness, these networks rely on transcriptional and post-transcriptional circuits involving both transcription factors (TFs) and microRNAs (miRNAs). The focus of this review is on RUNX1 (AML1), a master...

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Share to Acute Myeloid Leukemia Research
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PMID: 23344057
DOI: 10.3390/ijms14011566

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