Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interplay between Transcription Factors and the Epigenome: Insight from the Role of RUNX1 in Leukemia

29 Sept 2015

Abstract excerpt

The genome has the ability to respond in a precise and co-ordinated manner to cellular signals. It achieves this through the concerted actions of transcription factors and the chromatin platform, which are targets of the signaling pathways. Our understanding of the molecular mechanisms through which transcription factors and the chromatin landscape each control gene activity has expanded dramatically over recent...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Myeloid Leukemia Research
Share to Epigenetics and DNA Methylation
Share to Histone Deacetylase Inhibitors Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26483790
DOI: 10.3389/fimmu.2015.00499

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interplay between Transcription Factors and the Epigenome: Insight from the Role of RUNX1 in LeukemiaPMID 26483790Read ↗

RUNX1-ETO: Attacking the Epigenome for Genomic Instable LeukemiaSemantic proximity Read ↗

The genomic and epigenomic landscapes of AML.Semantic proximity Read ↗

t(8;21) Acute Myeloid Leukemia as a Paradigm for the Understanding of Leukemogenesis at the Level of Gene Regulation and Chromatin Programming.Semantic proximity Read ↗

Epigenetic Regulators in the Development, Maintenance, and Therapeutic Targeting of Acute Myeloid LeukemiaSemantic proximity Read ↗

Chromatin modifiers and the promise of epigenetic therapy in acute leukemia.Semantic proximity Read ↗

Epigenetics in Hematological Malignancies.Semantic proximity Read ↗

Depletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding.Semantic proximity Read ↗

Mechanisms of epigenetic regulation of leukemia onset and progression.Semantic proximity Read ↗

RUNX1-ETO and RUNX1-EVI1 Differentially Reprogram the Chromatin Landscape in t(8;21) and t(3;21) AML.Semantic proximity Read ↗

Normal and transforming functions of RUNX1: A perspectiveSemantic proximity Read ↗

RUNX transcription factors at the interface of stem cells and cancer.Semantic proximity Read ↗

Transcriptional networks in acute myeloid leukemiaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.