Article

A Powerful Method for Pleiotropic Analysis under Composite Null Hypothesis Identifies Novel Shared Loci Between Type 2 Diabetes and Prostate Cancer

2020-04-13

Abstract excerpt

<h4> S ummary </h4> There is increasing evidence that pleiotropy, the association of multiple traits with the same genetic variants/loci, is a very common phenomenon. Cross-phenotype association tests are often used to jointly analyze multiple traits from a GWAS. The underlying methods, however, are often designed to test the global null hypothesis that there is no association of a genetic variant with any of t...

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Literature Corpus work: dee7165e-86c6-5869-8cf6-d7dfcdf5997f
DOI: 10.1101/2020.04.11.037630

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