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Whole blood transcriptional responses associated with bacterial burden in pulmonary tuberculosis

2026-01-29

Abstract excerpt

<h4>Background</h4> Pulmonary TB (PTB) patients present with a wide range of pre-treatment Mycobacterium tuberculosis ( Mtb ) burdens, which predict poor treatment outcomes. We sought to identify immune pathways and biomarkers associated with pre-treatment Mtb burden. <h4>Methods</h4> We conducted whole-blood RNA sequencing in 295 Vietnamese adults with PTB, quantifying bacterial load using GeneXpert Ct valu...

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Literature Corpus work
deb0ba98-6880-557d-b0ed-ee3e37c57817
DOI
10.64898/2026.01.29.702471
Open publication

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Whole blood transcriptional responses associated with bacterial burden in pulmonary tuberculosisDOI 10.64898/2026.01.29.702471
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