Article

Genetic control of the transcriptional response to active tuberculosis disease and treatment

2025-08-29

Abstract excerpt

<title>Abstract</title> <p>The functional impact of genomic regulatory variation during active TB disease and anti-TB treatment (ATT) remains poorly understood. Here, using 240 paired whole-blood RNA-seq samples from n = 48 active TB patients who underwent ATT, we call and impute 1,506,948 genome-wide variants from these transcriptomes to map <italic>cis</italic>-expression quantitative trait loci (eQTL), respons...

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Literature Corpus work: 3eb4024b-4cd5-5fc9-bf82-d12b1ef93eb3
DOI: 10.21203/rs.3.rs-7311967/v1

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