Article

A whole-blood transcriptional signature associated with obstructive post-tuberculosis lung disease

2026-03-12

Abstract excerpt

<h4>Background</h4> Post-tuberculosis (TB) lung disease (PTLD) affects approximately 50% of persons with pulmonary TB. We recently discovered whole blood transcriptional signatures associated with PTLD. We examined whether a minimum gene signature predicts PTLD as a clinically useful biomarker. <h4>Methods</h4> We prospectively enrolled 301 treatment naïve adults with newly diagnosed pulmonary TB (PTB) (cohort A...

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Literature Corpus work: ef20b4cf-10a8-5cfc-bcb4-22807826bc27
DOI: 10.64898/2026.03.11.26348051

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