Article

Whole blood transcriptional profiles and the pathogenesis of tuberculous meningitis

2023-10-09

Abstract excerpt

<h4>Background</h4> Mortality and morbidity from tuberculous meningitis (TBM) are frequent and strongly associated with the inflammatory response to Mycobacterium tuberculosis infection. However, the mechanisms driving the associations are uncertain. We sought to identify the gene modules, hubs and pathways associated with the pathogenesis and mortality from TBM, and to identify which best-predicted death. <h4>...

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Literature Corpus work: 20cc985b-811a-5545-9ecd-3215af45dd9a
DOI: 10.1101/2023.10.06.561265

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