Article

Backtranslation of human RNA biosignatures of tuberculosis disease risk into the preclinical pipeline is condition dependent

2024-06-21

Abstract excerpt

It is not clear whether human progression to active tuberculosis disease (TB) risk signatures are viable endpoint criteria for evaluations of treatments in clinical or preclinical development. TB is the deadliest infectious disease globally and more efficacious vaccines are needed to reduce this mortality. However, the immune correlates of protection for either preventing infection with Mycobacterium tuberculosis...

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Literature Corpus work: 54bdcf19-776c-593a-9b43-669ea99fcf27
DOI: 10.1101/2024.06.21.600067

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