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Identification and evaluation of blood transcriptional biomarker for tuberculosis screening

6 Feb 2025

Abstract excerpt

OBJECTIVES: Non-sputum-based screening methods for active case finding are a priority for ending tuberculosis. We sought to identify and evaluate blood transcriptional biomarkers suitable for tuberculosis screening. METHODS: We integrated five blood RNA-seq datasets from global tuberculosis patients and identified genes that are differentially expressed between tuberculosis patients and healthy controls, using...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39922484
DOI: 10.1016/j.ijid.2025.107838

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