Article

Endothelial Leakiness Induced by Amyloid Protein Aggregation

2022-01-19

Abstract excerpt

<title>Abstract</title> <p>Alzheimer’s disease (AD) is a major cause of dementia debilitating the global ageing population. Current understanding of the AD pathophysiology implicates the aggregation of amyloid beta (Aβ) as causative to neurodegeneration, with tauopathies and neuroinflammation considered as other major culprits. Curiously, vascular endothelial barrier dysfunction is strongly associated with Aβ dep...

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Literature Corpus work: de96e4a1-8afd-508d-b9f6-9e9382f43e3a
DOI: 10.21203/rs.3.rs-1161788/v1

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