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The relationship between glycaemia, cognitive function, structural brain outcomes and dementia: A Mendelian randomization study in the UK Biobank

2020-05-12

Abstract excerpt

<h4>Aims</h4> To investigate the relationship between glycaemia and cognitive function, brain structure and incident dementia using bidirectional Mendelian randomisation (MR). <h4>Methods</h4> UK Biobank (n~500,000) individuals, aged 40-69 years at baseline. Our exposures were genetic instruments for type-2 diabetes (163 variants) and HbA 1c (52 variants) and our outcomes were reaction time (RT - milliseconds), vi...

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Literature Corpus work
de7866b6-66b4-5773-b5c5-d44768112f1d
DOI
10.1101/2020.05.07.20094110
Open publication

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The relationship between glycaemia, cognitive function, structural brain outcomes and dementia: A Mendelian randomization study in the UK BiobankDOI 10.1101/2020.05.07.20094110
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