Article

Testing for associations between HbA1c levels, polygenic risk, and brain health in UK Biobank (N=39,283)

2023-01-20

Abstract excerpt

<p>Objective: Type-2 diabetes (T2D) has been associated with poorer brain health, and glycated haemoglobin (HbA1c) levels is a diagnostic test for diabetes. The aim of this study was to investigate whether continuous HbA1c levels, and HbA1c polygenic risk scores (HbA1c-PRS) significantly associate with worse brain health independent of T2D diagnosis (vs. not), by examining brain structure and cognitive test scores...

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Literature Corpus work: 0ebcd55a-b7e6-50ff-aa0d-cc993c875d5e
DOI: 10.31234/osf.io/rywn3

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