Article

Causal Effects of Type 2 Diabetes and Glycemic Traits on Dementia and Stroke: A Mendelian Randomization Study including Imaging Endpoints

2025-06-13

Abstract excerpt

<h4>Aims/hypothesis</h4> Type 2 diabetes mellitus (T2D) and glycemic dysregulation have been associated with cognitive decline and cerebrovascular disease, but causal relationships remain uncertain. We used Mendelian randomization (MR) to investigate the potential causal effects of T2D and glycemic traits, including hemoglobin A1c (HbA1c), fasting glucose (FG), fasting insulin (FI), and 2-hour glucose (2h-glu), on...

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Literature Corpus work: 1b1b8037-044c-5cc6-a754-3e5bc5324264
DOI: 10.1101/2025.06.11.25329399

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