Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Type 2 diabetes, glycaemic traits, structural brain capacity and cognitive function: A Mendelian randomization analysis.

Diabetes, obesity & metabolism - 1 Sept 2024

Luo Manjun, Sun Mengting, Wang Tingting, Wei Jianhui, Ruan Xiaorui, Chen Kebin, Ou Jun, Chen Yige, Qin Jiabi

Abstract excerpt

AIM: To estimate the causal associations of type 2 diabetes and glycaemic traits with cognitive function, and to determine the potential mediating role of various brain imaging-derived phenotypes (IDPs) using Mendelian randomization (MR) analysis. METHODS: Using publicly available summary data, we performed a series of univariable and multivariable MR analysis to infer causality. Two-step MR analysis was then...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood Glucose
Share to Brain

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cognition

Share to Cognitive Dysfunction

Share to Diabetes Mellitus, Type 2

Share to Fasting

Share to Mendelian Randomization Analysis

Share to Proinsulin

Source

Identifiers

PMID: 38925590
DOI: 10.1111/dom.15702

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Type 2 diabetes, glycaemic traits, structural brain capacity and cognitive function: A Mendelian randomization analysis.PMID 38925590Read ↗

Causal Effects of Type 2 Diabetes and Glycemic Traits on Dementia and Stroke: A Mendelian Randomization Study including Imaging EndpointsSemantic proximity Read ↗

Relationship Between Glycemia and Cognitive Function, Structural Brain Outcomes, and Dementia: A Mendelian Randomization Study in the UK Biobank.Semantic proximity Read ↗

The relationship between glycaemia, cognitive function, structural brain outcomes and dementia: A Mendelian randomization study in the UK BiobankSemantic proximity Read ↗

Association Between Plasma LRG1 and Lower Cognitive Function in Asians With Type 2 Diabetes Mellitus.Semantic proximity Read ↗

Educational attainment protects against type 2 diabetes independently of cognitive performance: a Mendelian randomization study.Semantic proximity Read ↗

Causal Links of Type 2 Diabetes and Its Complications With Cortical Modification: A Mendelian Randomization and Mediation Analysis.Semantic proximity Read ↗

Diabetes mellitus, glycemic traits, and cerebrovascular disease: a Mendelian randomization studySemantic proximity Read ↗

Causal relationship between imaging-derived phenotypes and neurodegenerative diseases: a Mendelian randomization study.Semantic proximity Read ↗

Inferring Multi-Organ Genetic Causal Connections using Imaging and Clinical Data through Mendelian RandomizationSemantic proximity Read ↗

Cerebral glucose uptake and cognitive functions: A phenome-wide Mendelian randomization study.Semantic proximity Read ↗

Mendelian randomization study of diabetes and dementia in the Million Veteran ProgramSemantic proximity Read ↗

Type 2 Diabetes and Cognitive Status in the Health and Retirement Study: A Mendelian Randomization ApproachSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.