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Phospho-sRNA-seq reveals extracellular mRNA/lncRNA fragments as potential biomarkers in human plasma

2019-02-18

Abstract excerpt

Extracellular RNAs (exRNAs) in biofluids have attracted great interest as potential biomarkers. Whereas extracellular microRNAs (miRNAs) in blood plasma are extensively characterized, extracellular messenger RNAs (mRNA) and long noncoding RNAs (lncRNA) are less well-studied. We report that plasma contains fragmented mRNAs and lncRNAs that are largely missed by standard small RNA-seq protocols due to lack of 5’ pho...

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Literature Corpus work
de68a215-36e8-5eaf-89e0-670b06960afb
DOI
10.1101/553438
Open publication

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Phospho-sRNA-seq reveals extracellular mRNA/lncRNA fragments as potential biomarkers in human plasmaDOI 10.1101/553438
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