Article

Identification of protein-protected mRNA fragments and structured excised intron RNAs in human plasma by TGIRT-seq peak calling

2020-06-27

Abstract excerpt

<h4>Summary</h4> Human plasma contains >40,000 different coding and non-coding RNAs that are potential biomarkers for human diseases. Here, we used thermostable group II intron reverse transcriptase sequencing (TGIRT-seq) combined with peak calling to simultaneously profile all RNA biotypes in apheresis-prepared human plasma pooled from healthy individuals. Extending previous TGIRT-seq analysis, we found that hum...

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Literature Corpus work: beeacbe4-e720-5a63-a7f2-5ff9aadba4f0
DOI: 10.1101/2020.06.25.171439

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