Article

Longitudinal and large-scale monitoring of transcriptome and RBP-RNA interactome in living cells by engineered protein nanocages

2025-03-15

Abstract excerpt

Nondestructive sequencing of RNA from live cells is essential for monitoring and understanding dynamic biological processes. However, most existing RNA sequencing methods rely on cell lysis or fixation, limiting their applicability for longitudinal studies. Here, we introduce POND-seq ( P rotein nanocage-emp O wered N on- D estructive seq uencing), a novel approach that employs secretory protein nanocages fus...

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Literature Corpus work: 75dbed1a-1417-5b07-88de-71966f200a15
DOI: 10.1101/2025.03.13.642977

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