Article

Depletion-assisted multiplexed cell-free RNA sequencing reveals distinct human and microbial signatures in plasma versus extracellular vesicles

2023-02-03

Abstract excerpt

Cell-free long RNAs in human plasma and extracellular vesicles (EVs) have shown promise as biomarkers in liquid biopsy, despite their fragmented nature. To investigate these fragmented cell-free RNAs (cfRNAs), we developed a cost-effective cfRNA sequencing method called DETECTOR-seq ( de pletion-assisted multipl e xed c ell-free to tal R NA seq uencing). DETECTOR-seq utilized a meticulously tailored set of c...

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Literature Corpus work: 62fe5d88-8cb1-5c40-a342-e933248d08bb
DOI: 10.1101/2023.01.31.526408

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