Article

Systematic cross-study assessment of RNA-Seq experimental workflows for plasma cell-free transcriptome profiling

2025-07-14

Abstract excerpt

Plasma cell-free RNA (cfRNA) is a promising source of non-invasive biomarkers, but its clinical translation is hindered by technical challenges and a lack of protocol standardization, which compromises reproducibility and comparability across studies. There is a need for a systematic evaluation of existing cfRNA-Seq workflows to understand the drivers of technical variability. Here, we address this gap by performi...

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Literature Corpus work: 17a85a93-f1eb-59fa-9c98-98b7b148fab0
DOI: 10.1101/2025.07.10.664092

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