Article

RNA dicing regulates the expression of an oncogenic JAK1 isoform

2024-02-20

Abstract excerpt

mRNA transcripts have limited potential for protein synthesis, defined by their open reading frames 1 . However, recent advances have revealed a far more complex reality, in which the proteome exceeds the perceived limits of the transcriptome 2–6 exposing a significant gap in our understanding. Our prior studies have demonstrated that mRNA can undergo further processing, yielding truncated, uncapped mRNAs with t...

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Literature Corpus work: de619b9f-6d7b-5f52-843b-db071a72590e
DOI: 10.1101/2024.02.20.581186

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