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Exploring pseudouridylation: dysregulation in disease and therapeutic potential

3 Jun 2024

Abstract excerpt

Pseudouridine (Ψ), the most abundant RNA modification, plays a role in pre-mRNA splicing, RNA stability, protein translation efficiency, and cellular responses to environmental stress. Dysregulation of pseudouridylation is linked to human diseases. This review explores recent insights into the role of RNA pseudouridylation alterations in human disorders and the therapeutic potential of Ψ. We discuss the impact of...

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PMID: 38833893
DOI: 10.1016/j.gde.2024.102210

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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