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Article

Functional characterization of the human Dicer1e isoform reveals non-canonical RNA processing and context-dependent remodeling of cellular regulatory networks

2026-07-23

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> Alternative transcript isoforms contribute to functional diversification of the proteome by generating protein variants with distinct structural and regulatory properties. Dicer1e is a naturally occurring truncated protein isoform of human Dicer (hDicer) detected in both physiological and cancer-associated contexts; however, its biochemical activity and biolog...

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Literature Corpus work
6de2d0e2-0598-590f-bac7-09207528e5d1
DOI
10.21203/rs.3.rs-10281152/v1
Open publication

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Functional characterization of the human Dicer1e isoform reveals non-canonical RNA processing and context-dependent remodeling of cellular regulatory networksDOI 10.21203/rs.3.rs-10281152/v1
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