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Article

Gene of the month: DICER1: ruler and controller.

Journal of clinical pathology - 1 Feb 2021

Thunders Michelle, Delahunt Brett

Abstract excerpt

DICER1 is a highly conserved RNaseIII endoribonuclease that has a critical role in the biogenesis of microRNAs (miRNAs). miRNAs are small regulatory RNAs responsible for post-transcriptional gene silencing, controlling more than half of human protein-coding genes. This is achieved through the targeting and regulation of complementary RNA transcripts and has a well-documented role in post-transcriptional gene...

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Identifiers

PMID: 33293352
DOI: 10.1136/jclinpath-2020-207203

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