Article

APOBEC3G Splicing Defects in Nonhuman Primate Models Result in Disparate Viral Mutational Profiles Relative to Humans

2026-08-12

Abstract excerpt

<h4>ABSTRACT</h4> Nonhuman primates (NHPs), particularly macaques, are indispensable models for studying human infectious diseases due to their close immunological and physiological similarities. Understanding species-specific molecular differences is essential for maximizing the translational value of these models. Here we report that APOBEC3G (A3G) , a potent antiviral restriction factor and the major source o...

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Literature Corpus work: de0a8b29-a4c5-5815-bf5a-afb66f3c3629
DOI: 10.64898/2026.08.06.743345

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