Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comparative analysis of the antiretroviral activity of APOBEC3G and APOBEC3F from primates.

Virology - 25 May 2006

Zennou Véronique, Bieniasz Paul D

Abstract excerpt

APOBEC3G and APOBEC3F exhibit antiretroviral activity primarily as a consequence of their ability to deaminate cytidines in retroviral DNA. Here, we compare the properties of APOBEC3F and APOBEC3G from human, macaque, and African green monkey (AGM). While all APOBEC proteins tested exhibited anti-HIV-1 activity, human APOBEC3F was, surprisingly, 10- to 50-fold less potent than human APOBEC3G. However, similar...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-HIV Agents
Share to APOBEC-3G Deaminase
Share to Cytidine Deaminase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytosine Deaminase

Share to Gene Products, vif

Share to Macaca mulatta

Share to vif Gene Products, Human Immunodeficiency Virus

Share to Virus Assembly

Source

Identifiers

PMID: 16460778
DOI: 10.1016/j.virol.2005.12.035

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comparative analysis of the antiretroviral activity of APOBEC3G and APOBEC3F from primates.PMID 16460778Read ↗

Antiretroviral Activity and Vif Sensitivity of Rhesus Macaque APOBEC3 ProteinsSemantic proximity Read ↗

The host restriction factor APOBEC3G and retroviral Vif protein coevolve due to ongoing genetic conflict.Semantic proximity Read ↗

APOBEC3G Splicing Defects in Nonhuman Primate Models Result in Disparate Viral Mutational Profiles Relative to HumansSemantic proximity Read ↗

APOBEC3B and APOBEC3C are potent inhibitors of simian immunodeficiency virus replication.Semantic proximity Read ↗

A single amino acid difference in the host APOBEC3G protein controls the primate species specificity of HIV type 1 virion infectivity factor.Semantic proximity Read ↗

A single amino acid determinant governs the species-specific sensitivity of APOBEC3G to Vif action.Semantic proximity Read ↗

Differential anti-APOBEC3G activity of HIV-1 Vif proteins derived from different subtypes.Semantic proximity Read ↗

Human and Rhesus APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H Demonstrate a Conserved Capacity To Restrict Vif-Deficient HIV-1Semantic proximity Read ↗

Convergence and divergence in the evolution of the APOBEC3G-Vif interaction reveal ancient origins of simian immunodeficiency viruses.Semantic proximity Read ↗

Moderate Influence of Human APOBEC3F on HIV-1 Replication in Primary LymphocytesSemantic proximity Read ↗

Interactions of host APOBEC3 restriction factors with HIV-1 in vivo: implications for therapeuticsSemantic proximity Read ↗

A second human antiretroviral factor, APOBEC3F, is suppressed by the HIV‐1 and HIV‐2 Vif proteinsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.