Article

Single-cell epigenetic profiling reveals an interferon response-high program associated with <i>BAP1</i> deficiency in kidney cancer

2024-11-18

Abstract excerpt

<h4>ABSTRACT</h4> Renal cell carcinoma (RCC) is characterized by recurrent somatic mutations in epigenetic regulators, which stratify patients into clinically significant subgroups with distinct prognoses and treatment responses. However, the cell type-specific epigenetic landscape of RCC—broadly and in the context of these mutations—is incompletely understood. To investigate these open questions, we integrated s...

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Literature Corpus work: ddf49355-d328-5fcf-998b-7172e318957e
DOI: 10.1101/2024.11.15.623837

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Single-cell epigenetic profiling reveals an interferon response-high program associated with <i>BAP1</i> deficiency in kidney cancerDOI 10.1101/2024.11.15.623837Read

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