Article

Chromatin accessibility shapes tumor architecture and microenvironment in clear cell renal cell carcinoma

2022-08-08

Abstract excerpt

<title>Abstract</title> <p>The molecular landscape of clear cell renal cell carcinoma (ccRCC) has been annotated by a number of large-scale sequencing studies, complemented by recent proteomics efforts. However, these bulk analyses are limited by the diverse cell populations that compose these tumors. Here, we obtained single-nucleus RNA-seq (snRNA-seq) and ATAC-seq (snATAC-seq) data from 31 and 13 samples from c...

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Literature Corpus work: 85121119-44a9-5a78-8256-383162750589
DOI: 10.21203/rs.3.rs-229922/v1

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