Article

Epigenome-wide profiling in the dorsal raphe nucleus highlights cell-type-specific changes in <i>TNXB</i> in Alzheimer’s disease

2023-08-29

Abstract excerpt

Recent studies have demonstrated that the dorsal raphe nucleus (DRN) is among the first brain regions affected in Alzheimer’s disease. Hence, in this study we conducted the first comprehensive epigenetic analysis of the DRN in AD, targeting both bulk tissue and single isolated cells. The Illumina Infinium MethylationEPIC BeadChip array was used to analyze the bulk tissue, assessing differentially modified position...

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Literature Corpus work: ddd3f18c-395c-5d3c-944e-784ab62896a0
DOI: 10.1101/2023.08.28.555168

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Epigenome-wide profiling in the dorsal raphe nucleus highlights cell-type-specific changes in <i>TNXB</i> in Alzheimer’s diseaseDOI 10.1101/2023.08.28.555168Read

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