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Early epigenetic changes of Alzheimer’s disease in the human hippocampus

1 Apr 2020

Abstract excerpt

The discovery of new biomarkers would be very valuable to improve the detection of early Alzheimer’s disease (AD). DNA methylation marks may serve as epigenetic biomarkers of early AD. Here we identified epigenetic marks that are present in the human hippocampus from the earliest stages of AD. A previous methylome dataset of the human AD hippocampus was used to select a set of eight differentially methylated...

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PMID: 32233750
DOI: 10.1080/15592294.2020.1748917

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