Article

Serotonergic innervation and cortical progenitor regulation in human brain assembloids

2026-04-14

Abstract excerpt

Neuromodulatory signaling is classically associated with mature neural circuits, yet serotonergic projections reach the developing cortex prior to circuit formation, suggesting a role in early human cortical development. Here, we establish a human raphe–cortical assembloid platform by generating iPSC-derived hindbrain-patterned raphe organoids that produce serotonergic neurons and form projections into fused corti...

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Mosquito-borne diseases and control

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Literature Corpus work: ddc508ad-fe1e-5276-bcc4-db11e64bd1c0
DOI: 10.64898/2026.04.13.718159

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