Article

Single-cell genomics reveals region-specific developmental trajectories underlying neuronal diversity in the human hypothalamus

2021-07-20

Abstract excerpt

The development and diversity of neuronal subtypes in the human hypothalamus has been insufficiently characterized. We sequenced the transcriptomes of 40,927 cells from the prenatal human hypothalamus spanning from 6 to 25 gestational weeks and 25,424 mature neurons in regions of the adult human hypothalamus, revealing a temporal trajectory from proliferative stem cell populations to mature neurons and glia. Devel...

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Literature Corpus work: fc5e1ee3-d0c1-5480-b1db-ccdbf7c983c8
DOI: 10.1101/2021.07.20.453090

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