Back to search

Article

Spatial Transcriptomics Reveal Developmental Dynamics of the Human Cerebral Cortex and Striatum

2025-08-15

Abstract excerpt

<h4>Summary</h4> The human fetal brain undergoes morphological changes that contribute to the development of regional functionalities. However, the features of structural development, the underlying molecular and cellular signatures in the fetal brain remain unclear. With spatial transcriptomics and snRNA-seq, we identified 25 forebrain regions and characterized the dynamic changes in the cortex and striatum duri...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
b599f356-169a-56ac-aa35-1a68e342b8a1
DOI
10.1101/2025.08.14.670213
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Spatial Transcriptomics Reveal Developmental Dynamics of the Human Cerebral Cortex and StriatumDOI 10.1101/2025.08.14.670213
Spatiotemporal molecular dynamics of the developing human thalamusSemantic proximity
Comprehensive cell atlas of the first-trimester developing human brainSemantic proximity
An Atlas of Cortical Arealization Identifies Dynamic Molecular SignaturesSemantic proximity
Single-cell analysis of prenatal and postnatal human cortical developmentSemantic proximity
Cellular resolution anatomical and molecular atlases for prenatal human brainsSemantic proximity
Cell type-specific gene expression dynamics during human brain maturationSemantic proximity
Multi-omics identification of extracellular components of the fetal monkey and human neocortexSemantic proximity
Single-cell multi-omics analysis of lineage development and spatial organization in the human fetal cerebellumSemantic proximity
The single-cell and spatial transcriptional landscape of human gastrulation and early brain developmentSemantic proximity
A single cell transcriptomic analysis of human neocortical developmentSemantic proximity
Spatial Single-cell Analysis Decodes Cortical Layer and Area SpecificationSemantic proximity
Dynamic expression of NR2F1 and SOX2 in developing and adult human cortex: comparison with cortical malformationsSemantic proximity
Select a neighboring publication to make it the new centre.