Article

Structural basis for phosphatidylcholine synthesis by bacterial phospholipid <i>N</i> -methyltransferases

2024-11-28

Abstract excerpt

In phosphatidylcholine (PC)-containing bacteria, PC is synthesized by phospholipid N -methyltransferases (Pmts) and plays an important role in the interactions between symbiotic and pathogenic bacteria and their eukaryotic host cells. Pmts catalyze the SAM dependent three methylation reactions of the head group of phosphatidylethanolamine (PE) to form PC through monomethyl PE and dimethyl PE. However, the precise...

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Literature Corpus work: ddb71243-6b3f-557a-8392-3c91ceba45cb
DOI: 10.1101/2024.11.28.625837

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