Article

Optimizing cancer immunotherapy response prediction by tumor aneuploidy score and fraction of copy number alterations

2023-03-16

Abstract excerpt

<title>Abstract</title> <p>Identifying patients with low tumor mutation burden (TMB) that are likely to respond to cancer immunotherapy is an important, yet highly challenging clinical need. Using 3,139 patients across 17 different cancer types, we comprehensively studied the ability of two common copy number alteration (CNA) scores – the tumor aneuploidy score (AS) and the fraction of genome encompassed by copy...

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Literature Corpus work: ddb3d799-f302-5b37-a990-533119c9f528
DOI: 10.21203/rs.3.rs-2644875/v1

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