Article

Somatic copy number alterations profiling in non-small cell lung cancer and their correlation with clinical efficacy in first-line treatment

2025-11-13

Abstract excerpt

<title>Abstract</title> <p> <bold>Background:</bold> Immune checkpoint inhibitors (ICI) are the current standard-of-care first-line treatment for advanced non-small cell lung cancer (NSCLC) without actionable genomic alterations. Yet some patients do not achieve clinical benefit, underscoring the need for predictive biomarkers. High burden of somatic copy number alterations (SCNAs), including chromosomal arm- a...

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Literature Corpus work: 6f82d083-6cea-5240-a9ea-d1aef22f13ad
DOI: 10.21203/rs.3.rs-8056146/v1

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