Article

Fraction of copy-number alterations significantly predicts survival following immunotherapy in a few cancers

2022-12-29

Abstract excerpt

<h4>SUMMARY</h4> Various studies have shown that high tumor mutation burden (TMB) may predict response to immune checkpoint therapy, at least in some cancer types 1,2 . However, identifying patients with low TMB that are still likely to respond to cancer immunotherapy is an important open challenge. Recently, Spurr et al. 3 reported that the tumor aneuploidy score (AS), defined as the fraction of chromosome ar...

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Literature Corpus work: 02b07979-9f48-503c-ac06-cfa89229770f
DOI: 10.1101/2022.12.28.522101

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