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Article

hadge: a comprehensive pipeline for donor deconvolution in single-cell studies.

Genome biology - 26 Apr 2024

Curion Fabiola, Wu Xichen, Heumos Lukas, André Mylene Mariana Gonzales, Halle Lennard, Ozols Matiss, Grant-Peters Melissa, Rich-Griffin Charlotte, Yeung Hing-Yuen, Dendrou Calliope A, Schiller Herbert B, Theis Fabian J

Abstract excerpt

Single-cell multiplexing techniques (cell hashing and genetic multiplexing) combine multiple samples, optimizing sample processing and reducing costs. Cell hashing conjugates antibody-tags or chemical-oligonucleotides to cell membranes, while genetic multiplexing allows to mix genetically diverse samples and relies on aggregation of RNA reads at known genomic coordinates. We develop hadge (hashing deconvolution...

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Identifiers

PMID: 38671451
DOI: 10.1186/s13059-024-03249-z
PMCID: PMC11055383

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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