Article
APOL1 Renal Risk Variants: Fertile Soil for HIV-Associated Nephropathy.
Seminars in nephrology - 1 Nov 2017
Kopp Jeffrey B, Heymann Jurgen, Winkler Cheryl A
Abstract excerpt
Apolipoprotein L1 (APOL1) genetic variants are potent risk factors for glomerular disease, but one or more additional factors are required for expression of glomerular disease. Uncontrolled or poorly controlled human immunodeficiency virus (HIV) infection is the most potent susceptibility factor for APOL1 nephropathy that has been identified to date. APOL1 variants are associated with HIV-associated nephropathy...
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