Article

Beyond chromatin accessibility: bulk ATAC-seq as an integrative assay to portray genomes and epigenomes

2025-01-20

Abstract excerpt

<h4>ABSTRACT</h4> Assay for transposase-accessible chromatin using sequencing (ATAC-seq) is a cornerstone for epigenomic profiling, yet its potential for genomic characterization remains poorly explored. Here, we systematically benchmarked bulk ATAC-seq against whole-genome sequencing (WGS) to assess its capacity for detecting small variants, copy number variations (CNVs), telomere-associated repeat content, and...

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Literature Corpus work: 7fae4ca1-c93e-5ae0-8d91-2d5e98c52bed
DOI: 10.1101/2025.01.18.633115

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