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Article

SIMULATING TUMOR MITOCHONDRIAL ENERGETICS THROUGH ENGINEERING-STYLE ENERGY METRICS

2025-09-06

Abstract excerpt

<h4>ABSTRACT</h4> Cancer progression is linked to alterations in cellular energetics, where malignant cells reprogram their metabolism to sustain proliferation, resist stress and adapt to nutrient limitations. Beyond intrinsic adaptations and plastic dynamic switches between glycolysis and oxidative phosphorylation, recent work has shown that tumors actively remodel their microenvironment by acquiring functional...

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Literature Corpus work
dd38b807-369a-5ae4-86dd-2c6cf8b34333
DOI
10.1101/2025.09.02.673700
Open publication

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